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Fig. 2 | Breast Cancer Research

Fig. 2

From: Androgen receptor-mediated pharmacogenomic expression quantitative trait loci: implications for breast cancer response to AR-targeting therapy

Fig. 2

AR PGx-eQTL signals motif and cis-regulatory elements analysis. a Homer motif analysis of SNP periphery sequences from DHT/ENZ- induced PGx-eQTL signals, filtered by AR ChIPseq binding sites. Red text indicates classical AR binding motifs. b Piechart for SNPs locations relative to the corresponding PGx-eQTL genes, filtered by AR ChIPseq binding sites,. c Analysis of SNP-sites based ChromHMM cis-regulatory elements (RE) using all DHT/ENZ- induced PGx-eQTL signals, filtered by AR ChIPseq binding sites. X-axis indicates relative locations of SNPs to PGx-eQTL genes and color indicates cis-RE annotation by ChromHMM

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