Fig. 4
From: DNA methylation-predicted plasma protein levels and breast cancer risk
Protein EpiScores identified in the primary analysis of invasive breast cancer risk that showed significant heterogeneity by tumor ER status. Hazard ratios and 95% confidence intervals displayed only for Protein EpiScores that were significantly associated with invasive breast cancer incidence in the primary analysis and significantly modified by tumor ER status (interaction FDR < 0.15). Models treat age as the time-scale and are therefore adjusted for age. The models additionally include DNAm platform (HumanMethylation450, MethylationEPIC) and self-reported race (non-Hispanic White, Black) as covariates. Bolded Protein EpiScores are those that were designed to predict plasma proteins related to ‘immune response.’