|  |  | Recommended biopsy (%) | Unnecessary biopsies (%) ^ | AUC | Sensitivity (%) | Specificity (%) |
---|---|---|---|---|---|---|---|
All cases combined (n = 157) | US | R7 | 66.2 (104/157) | 32.7 (34/104) | 0.734 (0.654–0.814) | 89.7 (85.0-94.5) | 57.0 (49.2–64.7) |
R7 + DL-UM | 54.8 (86/157) | 14.0 (12/86) | 0.898 (0.844–0.953) | 94.9 (91.4–98.3) | 84.8 (79.2–90.4) | ||
R9 | 59.9 (94/157) | 24.5 (23/94) | 0.810 (0.739–0.881) | 91.0 (86.6–95.5) | 70.9 (63.8–78.0) | ||
R9 + DL-UM | 55.4 (87/157) | 12.6 (11/87) | 0.918 (0.868–0.967) | 97.4 (95.0-99.9) | 86.1 (80.7–91.5) | ||
MG | R8 | 64.3 (101/157) | 30.7 (31/101) | 0.753 (0.674–0.831) | 89.7 (85-9.49.0) | 60.8 (53.1–68.4) | |
R8 + DL-UM | 56.1 (88/157) | 13.6 (12/88) | 0.911 (0.860–0.963) | 97.4 (95.0-99.9) | 84.8 (79.2–90.4) | ||
R10 | 57.3 (90/157) | 21.1 (19/90) | 0.835 (0.768–0.902) | 91.0 (86.6–95.5) | 76.0 (69.3–82.6) | ||
R10 + DL-UM | 54.8 (86/157) | 12.8 (11/86) | 0.911 (0.860–0.963) | 96.2 (93.2–99.2) | 86.1 (80.7–91.5) | ||
concordant cases (n = 80) | US | R7 | 71.3 (57/80) | 19.3 (11/57) | 0.792 (0.680–0.904) | 93.9 (88.6–99.1) | 64.5 (54.0–75.0) |
R7 + DL-UM | 61.3 (49/80) | 6.1 (3/49) | 0.921 (0.849–0.993) | 93.9 (88.6–99.1) | 90.3 (83.8–96.8) | ||
R9 | 66.3 (53/80) | 11.3 (6/53) | 0.883 (0.794–0.972) | 95.9 (91.6-100.2) | 80.7 (72.0-89.3) | ||
R9 + DL-UM | 65.0 (52/80) | 7.7 (4/52) | 0.925 (0.852–0.999) | 98.0 (94.9-101.1) | 87.1 (79.8–94.4) | ||
MG | R8 | 71.3 (57/80) | 21.1 (12/57) | 0.766 (0.650–0.882) | 91.8 (85.8–97.8) | 61.3 (50.6–72.0) | |
R8 + DL-UM | 63.8 (51/80) | 5.9 (3/51) | 0.941 (0.876-1.000) | 98.0 (94.9-101.1) | 90.3 (83.8–96.8) | ||
R10 | 68.8 (55/80) | 12.7 (7/55) | 0.877 (0.784–0.969) | 98.0 (94.9-101.1) | 77.4 (68.3–86.6) | ||
R10 + DL-UM | 66.3 (53/80) | 9.4 (5/53) | 0.909 (0.828–0.990) | 98.0 (94.9-101.1) | 83.9 (75.8–91.9) | ||
discordant cases (n = 77) | US | R7 | 61.0 (47/77) | 48.9 (23/47) | 0.674 (0.552–0.796) | 82.8 (74.3–91.2) | 52.1 (40.9–63.2) |
R7 + DL-UM | 48.1 (37/77) | 24.3 (9/37) | 0.889 (0.811–0.967) | 96.6 (92.5-100.6) | 81.3 (72.5–90.0) | ||
R9 | 53.2 (41/77) | 41.5 (17/41) | 0.737 (0.622–0.851) | 82.8 (74.3–91.2) | 64.6 (53.9–75.3) | ||
R9 + DL-UM | 45.5 (35/77) | 20.0 (7/35) | 0.910 (0.839–0.981) | 96.6 (92.5-100.6) | 85.4 (77.5–93.3) | ||
MG | R8 | 57.1 (44/77) | 43.1 (19/44) | 0.733 (0.619–0.847) | 86.2 (78.5–93.9) | 60.4 (49.5–71.3) | |
R8 + DL-UM | 48.1 (37/77) | 24.3 (9/37) | 0.889 (0.811–0.967) | 96.6 (92.5-100.6) | 81.3 (72.5–90.0) | ||
R10 | 45.5 (35/77) | 34.3 (12/35) | 0.772 (0.660–0.883) | 79.3 (70.3–88.4) | 75.0 (65.3–84.7) | ||
R10 + DL-UM | 42.9 (33/77) | 18.2 (6/33) | 0.903 (0.826–0.980) | 93.1 (87.5–98.8) | 87.5 (80.1–94.9) |