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Table 2 Diagnostic performance and management recommendation improvement through DL-UM-radiologists collaboration

From: Optimizing breast lesions diagnosis and decision-making with a deep learning fusion model integrating ultrasound and mammography: a dual-center retrospective study

   

Recommended biopsy (%)

Unnecessary biopsies (%) ^

AUC

Sensitivity (%)

Specificity (%)

All cases combined

(n = 157)

US

R7

66.2 (104/157)

32.7 (34/104)

0.734 (0.654–0.814)

89.7 (85.0-94.5)

57.0 (49.2–64.7)

R7 + DL-UM

54.8 (86/157)

14.0 (12/86)

0.898 (0.844–0.953)

94.9 (91.4–98.3)

84.8 (79.2–90.4)

R9

59.9 (94/157)

24.5 (23/94)

0.810 (0.739–0.881)

91.0 (86.6–95.5)

70.9 (63.8–78.0)

R9 + DL-UM

55.4 (87/157)

12.6 (11/87)

0.918 (0.868–0.967)

97.4 (95.0-99.9)

86.1 (80.7–91.5)

MG

R8

64.3 (101/157)

30.7 (31/101)

0.753 (0.674–0.831)

89.7 (85-9.49.0)

60.8 (53.1–68.4)

R8 + DL-UM

56.1 (88/157)

13.6 (12/88)

0.911 (0.860–0.963)

97.4 (95.0-99.9)

84.8 (79.2–90.4)

R10

57.3 (90/157)

21.1 (19/90)

0.835 (0.768–0.902)

91.0 (86.6–95.5)

76.0 (69.3–82.6)

R10 + DL-UM

54.8 (86/157)

12.8 (11/86)

0.911 (0.860–0.963)

96.2 (93.2–99.2)

86.1 (80.7–91.5)

concordant cases

(n = 80)

US

R7

71.3 (57/80)

19.3 (11/57)

0.792 (0.680–0.904)

93.9 (88.6–99.1)

64.5 (54.0–75.0)

R7 + DL-UM

61.3 (49/80)

6.1 (3/49)

0.921 (0.849–0.993)

93.9 (88.6–99.1)

90.3 (83.8–96.8)

R9

66.3 (53/80)

11.3 (6/53)

0.883 (0.794–0.972)

95.9 (91.6-100.2)

80.7 (72.0-89.3)

R9 + DL-UM

65.0 (52/80)

7.7 (4/52)

0.925 (0.852–0.999)

98.0 (94.9-101.1)

87.1 (79.8–94.4)

MG

R8

71.3 (57/80)

21.1 (12/57)

0.766 (0.650–0.882)

91.8 (85.8–97.8)

61.3 (50.6–72.0)

R8 + DL-UM

63.8 (51/80)

5.9 (3/51)

0.941 (0.876-1.000)

98.0 (94.9-101.1)

90.3 (83.8–96.8)

R10

68.8 (55/80)

12.7 (7/55)

0.877 (0.784–0.969)

98.0 (94.9-101.1)

77.4 (68.3–86.6)

R10 + DL-UM

66.3 (53/80)

9.4 (5/53)

0.909 (0.828–0.990)

98.0 (94.9-101.1)

83.9 (75.8–91.9)

discordant cases

(n = 77)

US

R7

61.0 (47/77)

48.9 (23/47)

0.674 (0.552–0.796)

82.8 (74.3–91.2)

52.1 (40.9–63.2)

R7 + DL-UM

48.1 (37/77)

24.3 (9/37)

0.889 (0.811–0.967)

96.6 (92.5-100.6)

81.3 (72.5–90.0)

R9

53.2 (41/77)

41.5 (17/41)

0.737 (0.622–0.851)

82.8 (74.3–91.2)

64.6 (53.9–75.3)

R9 + DL-UM

45.5 (35/77)

20.0 (7/35)

0.910 (0.839–0.981)

96.6 (92.5-100.6)

85.4 (77.5–93.3)

MG

R8

57.1 (44/77)

43.1 (19/44)

0.733 (0.619–0.847)

86.2 (78.5–93.9)

60.4 (49.5–71.3)

R8 + DL-UM

48.1 (37/77)

24.3 (9/37)

0.889 (0.811–0.967)

96.6 (92.5-100.6)

81.3 (72.5–90.0)

R10

45.5 (35/77)

34.3 (12/35)

0.772 (0.660–0.883)

79.3 (70.3–88.4)

75.0 (65.3–84.7)

R10 + DL-UM

42.9 (33/77)

18.2 (6/33)

0.903 (0.826–0.980)

93.1 (87.5–98.8)

87.5 (80.1–94.9)

  1. Data are expressed as means and 95% confidence intervals in parentheses or as a count in parentheses. R7: junior radiologist in breast ultrasound; R8: junior radiologist in breast mammography; R9: senior radiologist in breast ultrasound; R10: senior radiologist in breast mammography. ^: Biopsies in benign lesions. Abbreviations: US, ultrasound; MG, mammography; BI-RADS, Breast Imaging Reporting and Data System; AUC, area under the receiver operating characteristic curve